Minnesota will need to slow play a clean/disciplined game and hope the Buckeye's make a lot of mistakes to negate big plays.
That's basically Big 10 West football (Iowa, Minny, N'Western, Wiscy). It's how they consistently beat Nebraska.
They don't have the talent of the East (tOSU, Mich, Penn St), so if they don't do stupid shit, they have a chance.
I'm not saying Nebraska has the talent of Ohio St (they don't), just that Nebraska has more talent than the other West teams, but consistently end up 4th or worse in the division by not paying attention to detail. i.e. Doing stupid shit.