Nah... As someone who is very leery of SC's defense at this point, I seriously doubt the USC/Buffs game will be anywhere near like that TCU/Buffs game. Even the ArizonaSt team, being as scrappy as they were against USC, looked like a much better team than the Buffs.
The Buff's defense is TOTALLY suspect and will leak like a sieve against good teams and SC will put up plenty of points and even SC's defense, such as it is, will probably actually look decent.
Now having said all that, I've been around when great SC teams have imploded against BAD teams like Stanford and OregonSt back in the Pete Carroll days. FUGLY!!!
Never say Never, but I think USC will win this game by a significant margin...

They may even actually "cover"...