"The two-disc special edition DVD, released in 2008, contains an alternate ending which more closely follows the novel.
[9]
During the lab attack, the alpha male Darkseeker creates a butterfly shape while attempting to break through the glass to the laboratory. Neville realizes it is referencing the butterfly-shaped tattoo on the female Darkseeker's neck and the alpha male is trying to recover his mate. Neville puts his gun down and returns the female. Neville and the alpha male stare each other down and Neville apologizes after seeing the latter emotionally break down upon his mate's return. Although the alpha male initially contemplates killing Neville, he forgives his former adversary and departs with the rest of the pack. Once they are gone, a shocked Neville looks over at the many photographs of his test subjects and realizes he has become a monster in the eyes of the infected, showing remorse for the experiments he has undertaken over the years.
The next morning, Neville abandons his research and heads along with Anna and Ethan to Vermont as a changed man, in the hope of finding the survivors' colony. They cross the
George Washington Bridge, while Anna delivers a hopeful monologue ending with the statement: "You are not alone."
[10][11][12][13][14]"
en.wikipedia.org
I have that DVD and I fully agree that the ending that followed the book closer was better.
