I think you're being really low on what Frederick brings to the table. The fit and chemistry is alot better with him on the court. Iowa was housing teams with him in the lineup. You beat Minnesota by 15, Purdue by 15, NW by 15 and 23. MD by 22 @MD. Swept Rutgers beating them by 13 this time around. I think when he went down with the injury Iowa was up to #3 in KenPom.
I honestly don't think Iowa is all that deep of a team. I only really trust 7 guys, sometimes 8 depending on how the other McCaffrey is playing. You take away a player avg 26.5 mpg prior to the injury, and have to put in his place a starter that doesn't fit the same, it weakens your starting 5, but also your bench.